Sfoglia Dipartimento di Farmacia e Scienze della Salute e della Nutrizione - Tesi di Dottorato per Soggetto "Cancer"
Items 1-4 di 4
-
Action of the E2/ERβ/PTEN signaling in the metabolic reprogramming of TCam 2, human melanoma cell line
(2019-03-21)I tumori maligni più abbondanti nella popolazione maschile di età compresa tra i 17 ed i 45 anni, sono i tumori delle cellule germinali (GCTs). Essi comprendono un gruppo eterogeneo di neoplasie in termini istologici, ... -
Activated FXR inhibits leptin signaling and counteracts tumor-promoting activities of cancer-associated fibroblasts in breast malignancy
(2017-06-12)Cancer-associated fibroblasts (CAFs), the principal components of the tumor stroma, play a central role in cancer development and progression. As an important regulator of the crosstalk between breast cancer cells and CAFs, ... -
Estrogen receptor alpha interferes with LKBl/AMPK/mTOR signaling activation in adiponectin-treated breast cancer cells
(2018-02-27)Breast cancer is the most common type of tumor and the leading cause of cancer-related deaths in women, worldwide. The cause of breast cancer is multifactorial and includes hormonal, genetic and environmental cues. Obesity ... -
Role of ERalpha/NOTCH4 axis in sustaining stemness in breast cancer cells
(2018-02-27)Early detection and new therapeutic strategies have improved breast cancer patient outcome and survival rates in the last years. However, breast cancer still remains the second leading cause of cancer-related deaths among ...