Sfoglia Dipartimento di Farmacia e Scienze della Salute e della Nutrizione - Tesi di Dottorato per Autore "Andò, Sebastiano"
Items 21-29 di 29
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Preclinical and mechanistic studies of small-molecule drugs targeting stat3
Badolato, Mariateresa; Andò, Sebastiano; Garofalo, Antonio; Aiello, Francesca (2018-02-27) -
Progesterone Receptor B disrupts the metabolic reprogramming in breast cancer cell lines producing death by blocking energy producing pathways, and p53 may be linked in this tumour suppressive-action
Santoro, Marta; Andò, Sebastiano; Aquila, Saveria (Università della Calabria, 2021-11-10)Il carcinoma mammario (BC) rappresenta la più comune causa di morte per neoplasia nella donna. Nonostante i progressi fatti nella diagnosi precoce e nella terapia, esso resta una delle forme tumorali con prognosi infausta. ... -
Role of ERalpha/NOTCH4 axis in sustaining stemness in breast cancer cells
Elena Spina, Elena Spina; Andò, Sebastiano (2018-02-27)Early detection and new therapeutic strategies have improved breast cancer patient outcome and survival rates in the last years. However, breast cancer still remains the second leading cause of cancer-related deaths among ... -
Role of PPARy in the complex interplay between brest cancer cells and tumor microenvironment
Gionfriddo, Giulia; Andò, Sebastiano; Bonofiglio, Daniela (2019-03-21)Stromal Derived Factor-1α (SDF-1α) and its cognate receptor CXCR4 play a key role in mediating breast cancer cell invasion and metastasis. Therefore, drugs able to inhibit CXCR4 activation may add critical tools to reduce ... -
Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells
Avino, Silvia; Andò, Sebastiano; Maggiolini, Marcello (2017-06-12)Insulin-like growth factor-I (IGF-I)/IGF-I receptor (IGF-IR) system has been largely involved in the pathogenesis and development of various tumors. We have previously demonstrated that IGF-IR cooperates with the G-protein ... -
Stromal cells in breast cancer microenvironment: molecular mechanisms involved in tumor progression and potential therapeutic targets
Augimeri, Giuseppina; Andò, Sebastiano; Bonofiglio, Daniela; Kleer, Celina (Università della Calabria, 2021-03-26)Stromal cells in the tumor microenvironment (TME) play an important role in breast cancer progression, metastasis and therapeutic outcome. Among stromal cells, Tumor-Associated Macrophages (TAMs) and Mesenchymal Stem Cells ... -
Study of antimicrobial and anticancer activity of new synthetic and natural tools
Dhanyalayam, Dhanya; Andò, Sebastiano; Cappello, Anna Rita (2017-06-12)Infectious diseases and cancer are the two disease groups that representing the major cause of death worldwide. Unfortunately, antibiotic resistance is the biggest threat in the first case; in fact, new resistance ... -
T3/TRPr indaces proltferutive effects on pupillury thyroid cuncer cells FB2
Perri, Anna; Sisci, Diego; Andò, Sebastiano (2013-07-01) -
Targeting systems vulnerabilities in uveal melanoma by CRISPR Cas/9 focal adhesion kinase (FAK) genome editing and therapeutic inhibition
Rigiracciolo, Damiano Cosimo; Andò, Sebastiano; Maggiolini, Marcello (2018-02-27)Il Melanoma Uveale rappresenta la neoplasia intraoculare più frequente nell’età adulta. Colpisce circa 2,500 individui ogni anno negli USA ed il 50% dei pazienti affetti da tale neoplasia sviluppa metastasi entro 5 ...