• Chemical modifications of polyphenols for the development of new molecules foods for the treatment of metabolic disorders 

  Carullo, Gabriele; Andò, Sebastiano; Aiello, Francesca (Università della Calabria, 2020-07-01)

  Metabolic disorders represent the principal cause of death in the industrialized world, affecting several people, because of their incorrect lifestyle. Among them, Type 2 Diabetes Mellitus and related comorbidities, such ...

• Advanced functionalized materials for multipurpose applications 

  Pantuso, Elvira; Andò, Sebastiano; Nicoletta, Fiore (Università della Calabria, 2021-03-21)

• Sistemi polimerici multicomponente per la veicolazione di principi attivi 

  Farfalla, Annafranca; Andò, Sebastiano; Iemma, Francesca (Università della Calabria, 2021-02-25)

  L’attività di ricerca riportata nel presente lavoro di tesi di dottorato si inserisce nel contesto della sintesi e caratterizzazione di materiali multifunzionali per la veicolazione e il direzionamento di principi ...

• Evidence that ANG II/AGTR1 signaling stimulates aromatase activity, enhances local estrogen production involved in Glioblastoma cell growth and progression 

  Russo, umberto; Andò, Sebastiano; De Amicis, Francesca (Università della Calabria, 2021-04-01)

• Progesterone Receptor B disrupts the metabolic reprogramming in breast cancer cell lines producing death by blocking energy producing pathways, and p53 may be linked in this tumour suppressive-action 

  Santoro, Marta; Andò, Sebastiano; Aquila, Saveria (Università della Calabria, 2021-11-10)

  Il carcinoma mammario (BC) rappresenta la più comune causa di morte per neoplasia nella donna. Nonostante i progressi fatti nella diagnosi precoce e nella terapia, esso resta una delle forme tumorali con prognosi infausta. ...

• Application of computational methodologies toward the identification of novel therapeutics and photodegradation studies for the design of light-stable formulations 

  Occhiuzzi, Maria Antonietta; Andò, Sebastiano; Grande, Fedora; Iole, Giuseppina (Università della Calabria, 2021-06-10)

• Charatterization of store-operated calcium entry in the neuroimmune response evoked by ischemic preconditioning in mice subjected to middle cerebral artery occlusion 

  Frisina, Marialaura; Andò, Sebastiano; Amantea, Diana (Università della Calabria, 2021-06-10)

  Cerebral ischemia is one of the leading causes of death and long-term disability worldwide. Currently approved therapies for ischemic stroke are limited to reperfusion through mechanical recanalization and/or pharmacological ...

• Stromal cells in breast cancer microenvironment: molecular mechanisms involved in tumor progression and potential therapeutic targets 

  Augimeri, Giuseppina; Andò, Sebastiano; Bonofiglio, Daniela; Kleer, Celina (Università della Calabria, 2021-03-26)

  Stromal cells in the tumor microenvironment (TME) play an important role in breast cancer progression, metastasis and therapeutic outcome. Among stromal cells, Tumor-Associated Macrophages (TAMs) and Mesenchymal Stem Cells ...

• GPER mediates the up-regulation of acid synthase (fasn) intuced by 17B-estradiol in cancer cell and in cancer-associated fibroblasts (CAFs) 

  Santolla, Maria Francesca; Maggiolini, Marcello; Sisci, Diego (2012-11-26)

  Activation of lipid metabolism is an early event in carcinogenesis and a central hallmark of many tumors. Fatty acid synthase (FASN) is a key lipogenic enzyme catalyzing the terminal steps in the de novo biogenesis of ...

• FoxO3a reactivation restores the sensitivity to the antiestrogen treatment in tamoxifen resistant breast cancer 

  Donà, Ada Alice; Andò, Sebastiano; Sisci, Diego (2017-06-12)

  Resistance to endocrine treatments is a major clinical challenge in the management of estrogen receptor alpha positive (ER+) breast cancers (BC). Although multiple mechanisms leading to endocrine resistance have been ...

• Activated FXR inhibits leptin signaling and counteracts tumor-promoting activities of cancer-associated fibroblasts in breast malignancy 

  Vircillo, Valentina; Andò, Sebastiano; Catalano, Stefania (2017-06-12)

  Cancer-associated fibroblasts (CAFs), the principal components of the tumor stroma, play a central role in cancer development and progression. As an important regulator of the crosstalk between breast cancer cells and CAFs, ...

• Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells 

  Avino, Silvia; Andò, Sebastiano; Maggiolini, Marcello (2017-06-12)

  Insulin-like growth factor-I (IGF-I)/IGF-I receptor (IGF-IR) system has been largely involved in the pathogenesis and development of various tumors. We have previously demonstrated that IGF-IR cooperates with the G-protein ...

• Idrogel funzionali per la veicolazione di principi attivi 

  Spataro, Tania; Andò, Sebastiano; Picci, Nevio (2017-06-12)

• Identification and biochemical-molecular characterization of mitochondrial carrier proteins in human andmodel organisms and associated diseases 

  Muto, Luigina; Andò, Sebastiano; Dolce, Vincenza (2017-06-12)

  The mitochondrial carriers (MCs) are transmembrane proteins found in the mitochondrial inner membrane, which catalyze the translocation of solutes through the membrane. These belong to a family of carrier proteins, the ...

• Development, accreditation and application of a confirmatory method for the determination of mercury in biological matrices:results of a biomonitoring study 

  Domanico, Francesco; Pezzi, Vincenzo (2017-06-12)

• Study of antimicrobial and anticancer activity of new synthetic and natural tools 

  Dhanyalayam, Dhanya; Andò, Sebastiano; Cappello, Anna Rita (2017-06-12)

  Infectious diseases and cancer are the two disease groups that representing the major cause of death worldwide. Unfortunately, antibiotic resistance is the biggest threat in the first case; in fact, new resistance ...

• Role of ERalpha/NOTCH4 axis in sustaining stemness in breast cancer cells 

  Elena Spina, Elena Spina; Andò, Sebastiano (2018-02-27)

  Early detection and new therapeutic strategies have improved breast cancer patient outcome and survival rates in the last years. However, breast cancer still remains the second leading cause of cancer-related deaths among ...

• Targeting systems vulnerabilities in uveal melanoma by CRISPR Cas/9 focal adhesion kinase (FAK) genome editing and therapeutic inhibition 

  Rigiracciolo, Damiano Cosimo; Andò, Sebastiano; Maggiolini, Marcello (2018-02-27)

  Il Melanoma Uveale rappresenta la neoplasia intraoculare più frequente nell’età adulta. Colpisce circa 2,500 individui ogni anno negli USA ed il 50% dei pazienti affetti da tale neoplasia sviluppa metastasi entro 5 ...

• Estrogen receptor alpha interferes with LKBl/AMPK/mTOR signaling activation in adiponectin-treated breast cancer cells 

  Naimo, Giuseppina Daniela; Andò, Sebastiano; Panno, Maria Luisa; Mauro, Loredana (2018-02-27)

  Breast cancer is the most common type of tumor and the leading cause of cancer-related deaths in women, worldwide. The cause of breast cancer is multifactorial and includes hormonal, genetic and environmental cues. Obesity ...

• Advanced materials for pharmaceutical and biomedical purposes 

  Mellace, Silvia; Andò, Sebastiano; Cassano, Roberta (2018-02-27)

  L'innovazione nella chimica dei materiali e nella nanotecnologia hanno sinergicamente contribuito all'avanzamento e allo sviluppo dei Drug Delivery Systems (DDS) creando devices in grado di proteggere farmaci e sostanze ...

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