Tesi di Dottorato: Recent submissions
Items 221-240 di 1616
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Role of ERalpha/NOTCH4 axis in sustaining stemness in breast cancer cells
(2018-02-27)Early detection and new therapeutic strategies have improved breast cancer patient outcome and survival rates in the last years. However, breast cancer still remains the second leading cause of cancer-related deaths among ... -
Targeting systems vulnerabilities in uveal melanoma by CRISPR Cas/9 focal adhesion kinase (FAK) genome editing and therapeutic inhibition
(2018-02-27)Il Melanoma Uveale rappresenta la neoplasia intraoculare più frequente nell’età adulta. Colpisce circa 2,500 individui ogni anno negli USA ed il 50% dei pazienti affetti da tale neoplasia sviluppa metastasi entro 5 ... -
Estrogen receptor alpha interferes with LKBl/AMPK/mTOR signaling activation in adiponectin-treated breast cancer cells
(2018-02-27)Breast cancer is the most common type of tumor and the leading cause of cancer-related deaths in women, worldwide. The cause of breast cancer is multifactorial and includes hormonal, genetic and environmental cues. Obesity ... -
Advanced materials for pharmaceutical and biomedical purposes
(2018-02-27)L'innovazione nella chimica dei materiali e nella nanotecnologia hanno sinergicamente contribuito all'avanzamento e allo sviluppo dei Drug Delivery Systems (DDS) creando devices in grado di proteggere farmaci e sostanze ... -
Advanced mass spectrometric approaches for the determination of food quality and development of new methodologies for enrichment of nutraceuticals in functional foods
(2018-02-27)The research works presented in this Ph.D. thesis are based on the nutraceuticals and functional foods research. The first part of the thesis deals with three main topics: 1. Structural characterization of new HMG-flavonoids ... -
Design and implementation of a modern ASP grounder
(2018-01-19)Answer Set Programming (ASP) is a declarative programming paradigm proposed in the area of non-monotonic reasoning and logic programming in the late '80 and early '90. Thanks to its expressivity and capability of dealing ... -
Topics in metric fixed point teory and stability of dynamical systems
(2018-01-19)In this thesis we introduce iterative methods approximating fixed points for nonlinear operators defined in infinite-dimensional spaces. The starting points are the Implicit and Explicit Midpoint Rules generating polygonal ... -
Seamless acceleratin numerical regular grid methods on manycore systems
(2018-01-19)Over the last two decades, a lot has changed regarding the way modern scientific applications are designed, written and executed, especially in the field of data-analytics, scientific computing and visualization. Dedicated ... -
Logic Programming in non-conventional environments
(2018-05-03)Logic Programming became a very useful paradigm in many different areas and thus several languages (and solvers) have been created to support various kinds of reasoning tasks. However, in the last decades, thanks also ... -
Tools and Techniques for Easing the Application of Answer Set Programming
(2018-01-19)Answer Set Programming (ASP) is a well-established declarative problem solving paradigm; it features high expressiveness and the ability to deal with incomplete knowledge, so it became widely used in AI and it is now ... -
Synthesis of high value added molecules by catalytic and heterocyclization approaches
(2018-05-11)In the present PhD thesis is reported the development of new sustainable catalytic processes for the production of high value added molecules starting from simple and readily available building blocks, under safer and ... -
Compositional and textural study of beach sands from active volcanic areas (southern tyrrhenian sea)
(2018-05-11)The main goal of this research focuses on the provenance, compositional and textural investigation of modern sand supplied from volcanic terrains (southern Tyrrhenian sea). This is a contribution to quantify the controls ... -
New composite materials for masonry rehabilitatiom: SRG and FRCM mechanical characterization
(2018-06-01)La caratterizzazione meccanica dei materiali è un processo necessario per la standardizzazione della metodologia di prova, per determinare le proprietà dei materiali necessarie per la progettazione e per valutare le loro ... -
Reverse electrodialysis for energy recovery: material development and performance evalution
(2018-05-11)Salinity Gradient Power- Reverse Electrodialysis (SGP-RED), so-called blue energy, is a promising untapped membrane based renewable and sustainable energy generation technology. Salinity gradient energy can be defined as ...