Tesi di Dottorato: Recent submissions
Items 141-160 di 1616
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Impact of DNA methylation on plant growth and development: a study on a methylation-defective mutant of Arabidopsis thaliana
(2017-06-09)Epigenetic modifications of DNA contribute to chromatin remodeling process and gene expression regulation playing a relevant role on the development of eukaryotic organisms. DNA methylation is an important epigenetic mark ... -
Eco-friendly extraction of bioactive compounds from olive (drupes and leaves), Stevia and Schizochytrium sp.
(2017-04-13)The use of nutraceutical compounds, as well as their extraction from natural sources, is now the subject of studies in various sectors. The research groups working in this field focus their attention on the optimization ... -
FoxO3a reactivation restores the sensitivity to the antiestrogen treatment in tamoxifen resistant breast cancer
(2017-06-12)Resistance to endocrine treatments is a major clinical challenge in the management of estrogen receptor alpha positive (ER+) breast cancers (BC). Although multiple mechanisms leading to endocrine resistance have been ... -
Activated FXR inhibits leptin signaling and counteracts tumor-promoting activities of cancer-associated fibroblasts in breast malignancy
(2017-06-12)Cancer-associated fibroblasts (CAFs), the principal components of the tumor stroma, play a central role in cancer development and progression. As an important regulator of the crosstalk between breast cancer cells and CAFs, ... -
Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells
(2017-06-12)Insulin-like growth factor-I (IGF-I)/IGF-I receptor (IGF-IR) system has been largely involved in the pathogenesis and development of various tumors. We have previously demonstrated that IGF-IR cooperates with the G-protein ... -
Idrogel funzionali per la veicolazione di principi attivi
(2017-06-12) -
Transition metal-based complexes as chemitherapeutic agents. Theoretical investigation of MoA, interaction with biological molecules and environmental conditions
(2017-05-05)Molti metalli e, conseguentemente, molti complessi metallici svolgono ruoli importanti all’interno di sistemi biologici e biochimici. Oggigiorno, è risaputo che essi rappresentano ingredienti molto importanti per la vita ... -
Computational study of new drugs for photodynamic therapy
(2017-05-05)Photodynamic'therapy'(PDT)'is'a'non:invasive'therapeutic'technique' for' the' treatment' of' different' kind' of' tumours' through' the' production' of' reactive'oxygen'species'(ROS)'that'act'as'cytotoxic'agents.'''' PDT'works' ... -
Identification and biochemical-molecular characterization of mitochondrial carrier proteins in human andmodel organisms and associated diseases
(2017-06-12)The mitochondrial carriers (MCs) are transmembrane proteins found in the mitochondrial inner membrane, which catalyze the translocation of solutes through the membrane. These belong to a family of carrier proteins, the ... -
New non invasive conservation methods for cultural heritage
(2017-06-12) -
Study of antimicrobial and anticancer activity of new synthetic and natural tools
(2017-06-12)Infectious diseases and cancer are the two disease groups that representing the major cause of death worldwide. Unfortunately, antibiotic resistance is the biggest threat in the first case; in fact, new resistance ... -
Ontology-driven information extraction
(2017-07-20)Information Extraction consists in obtaining structured information from unstructured and semi-structured sources. Existing solutions use advanced methods from the field of Natural Language Processing and Artificial ... -
CORE: an intelligent trasportation systems in Calabria
(2017-02-22) -
Paracoherent Answer Set Programming
(2017-02-22)L’Answer Set Programming (ASP) è un paradigma di programmazione dichiarativa basato sulla semantica dei modelli stabili. L’idea alla base di ASP è di codificare un problema computazionale in un programma logico i cui ... -
<<The>> impact of software on Mathematics education in high schools
(2017-02-22)Il rapporto tra tecnologia e insegnamento-apprendimento della Matematica è un fenomeno complesso che merita di essere osservato da diversi punti di vista. Uno di questi è il ruolo che i software svolgono, e potrebbero ... -
Pure strategies in security games
(2017-07-20)In the past decades game theory allowed to model mathematically conflicts between groups of players, each with their own agenda, and found ways to apply them in real life situations. One of such applications, which has ... -
Stima della produzione solida in bacini idrografici con differenti caratteristiche mediante l'applicazione del modello EPM
(2017-07-12)In order to increase the knowledge of sediment production and transport at the river basin scale, the research aims at the creation of a GIS project based on the multiparametric equation related to the potential erosion ... -
Innovative UV-LED polymerised bicontinuous microemulsion coating for membranes with special emphasis on MBRs
(2017-07-11)The main objective of this work is the preparation of polymerisable bicontinuous microemulsion (PBM) coatings applied onto commercial membranes for improving the anti-fouling properties and performance, in terms of water ...